Astral Dog
Member
I thought something was off about Wesker on RE 5, and not just his personality, the game doesn't do anything about the Umbrella revival hinted at the end of 4 , it appears Wesker was building something else, then he learns about his origins and takes the plan of Spencer instead.RE5 Wesker was campy and theatrical, but his motives were still in line with his character as defined in the (poorly translated) first game and REmake. His personality changed, which you could possibly explain as a result of his biological change, but his philosophy and agenda remained consistent.
He basically thinks that humans are lesser beings in the grand scheme of things and deserve to be usurped by 'superior' lifeforms, hence him falling in love with Tyrant, chasing Alexia to the Antarctic, sending Ada after the Plagas, and creating Uroboros.