Will SC5 really be Origin-exclusive? From the most recent titles it feels more like it's aimed at the core gamer crowd who doesn't really care too much about running a client. Or they could use the wider appeal to boost their numbers. I dunno.
Also, I dread that it's going to be in full (more or less) 3D, because that will just kill modding. Part of the appeal of modding in SC4 is that only the terrain was 3D and the lots were mostly just sprites with 4 different faces (for camera rotation) and possibly night lights. That meant that modders could actually put large amounts of detail into their lots because in the end the polygon count and texture sizes wouldn't matter. This is clearly different if the game is going to use full 3D buildings, possibly with greater camera control.
But I am still excited but I hope they do right by the modding community especially who do fantastic work. Too bad they happen to be jerks about it.