The 4 new skill slots will need a lot of points. I used the preview vids to work the following out:
1 slot - Research 2 mutations - 4 skill pts
2 slots - Research 4 mutations - 9 skill pts
3 slots - Research 8 mutations - 21 skill pts
4 slots - Research 12(?) mutations - 35 skill pts
Inner ring with 3 mutations need 2 points each to be researched.
Middle ring with 7 mutations need 3 points each to be researched.
Outer ring with 2 mutations need 4(?) points each to the researched.