Microsoft Studios / Xbox:
- Halo 5: Guardians gameplay demo (conference opener, Release: October 2015)
- Forza Motorsport 6 (gameplay debut, trailer. Release: September 2015)
- Fable Legends (trailer, gameplay features. Release: August 2015)
- Killer Instinct: Season 3 (trailer. Release: October 2015)
- Rise of the Tomb Raider (gameplay demo. Release: November 2015)
- The Division (gameplay demo. Release: November 2015)
- ID@Xbox sizzle reel, featuring: (Xbox One and Windows 10)
--- Gigantic
--- Inside
--- Ashen
--- Divinity: Original Sin
--- Cuphead
--- Space Engineers
--- Below
--- Superhot
- Age of Empires IV (gameplay debut trailer, coming in 2016 to Windows 10 and Xbox One)
- Quantum Break (trailer, coming in spring 2016)
- Crackdown (gameplay debut trailer, coming in 2016)
- Scalebound (gameplay debut trailer, coming in 2016)
- Battletoads coming to Project Spark
- New Battletoads game, developed by Twisted Pixel Games (coming in 2016)
- New Banjo Kazooie game, developed by Rare (coming in 2016)
- Gears of War (Xbox One edition, gameplay trailer, coming in 2016)
- Gears of War IV (teaser trailer, conference closer)
EA:
- Star Wars: Battlefront (gameplay debut and multiplayer demo, conference opener. Release: November 2015)
- FIFA 16 (trailer)
- Madden NFL 16 (trailer)
- Rory McIlroy PGA Tour (trailer)
- Need for Speed: Underground (trailer. Release: November 2015)
- Mirror's Edge (teaser trailer, coming in 2016)
- Mass Effect (teaser trailer, coming in 2016)
- New extreme racing game by Criterion Games. First-person, has ATV's, boats, helicopters etc (teaser trailer, coming in 2016)
- New Star Wars game by Visceral Games. Story-driven 3rd person action-adventure game (short teaser trailer, coming in early 2017)
Ubisoft:
- Assassin's Creed: Victory (cinematic trailer, gameplay trailer. Release: October 2015)
- Tom Clancy's: The Division (gameplay trailer and gameplay demo. Release: November 2015)
- Tom Clancy's: Rainbow Six: Siege (gameplay trailer and gameplay demo. Release October 2015)
- Toy Soliders: War Chest (trailer. Release: August 2015)
- Child of Light 2 (trailer. Release: early 2016)
- Just Dance 2016 (trailer and demo. Release: fall 2015)
- Anno 2204 (trailer. Release: fall 2015)
- Rayman 4 (trailer, coming in 2016)
- Beyond Good & Evil 2 (trailer, coming in 2016)
Square Enix:
- Deus Ex: Mankind Divided (debut gameplay demo, coming in 2016)
- Rise of the Tomb Raider (trailer, coming November 2015)
- New Hitman game (trailer, coming in 2016)
- Just Cause 3 (gameplay demo, coming in October 2015)
- Star Ocean 5 (trailer, coming in 2016)
- Final Fantasy XV (trailer, coming in 2016)
- Kingdom Hearts III (teaser trailer, coming in early 2017)
Bethesda Softworks:
- Doom (debut gameplay demo, coming in 2016)
- BattleCry (trailer, release date: 2015)
- The Elder Scrolls Online: Tamriel Unlimited (new content and features trailer)
- Dishonored 2 (trailer, coming in 2016)
- Fallout 4 (trailer, coming in 2016)