It would be awesome if you had to manage an earth and moon base at the same time, and need resources from each other to grow both of them.
Kind of like the occidental/oriental settlements in anno 1404.
I can't imagine that is *not* how it works. I imagine moon colonies will be similar to underwater ones in 2070, maybe with slightly more expanded construction options. The trade ships headed towards earth in the trailer pretty much tell you all you need to know anyway, they will exist side by side for sure.