I hope we get an answer/elaboration on the Skill/Perk situation.
We know there isn't a Skill section in the PipBoy anymore, but they definitely still seem to exist in some way, so it's not likely they're gone. Simply they could have changed the layout to be more like Skyrim's skill trees. So we still might have points in them 1-100, just they will be tied more into how our Perks are acquired and in the Perk list. This is supported the most by the fact that there is a dedicated button for the Perk Chart, possibly shown below in the second image from the initial reveal trailer.
We also saw the Perks poster in the initial trailer. There are 70 perks in total it seems from this and on the top row are the 7 SPECIAL attributes, while the left most column is too blurry to see. It's not clear if each column of Perks is associated with the SPECIAL they are under or to the left most column. I first thought the left column could be the Skills themselves, but there are only 10 and it's pretty certain there will be 13 Skills again due to the new gameplay showing the Vault Boy bobble head display has 20 slots in total; 7 for SPECIAL and 13 for Skills.
If they do create Skyrim like setup for FO4 and there 70 Perks in total, that would mean there are 5-6 perks per Skill. This though may also presents the issue of DLC since every DLC for FO3 and NV added in several perks so I wonder how that would work in this hypothetical new system. As well as just the passive perks you can acquire from certain actions within the story and achievements in the game.