Eurogamer say this about Resident Evil 5 on Move:
Resident Evil 5
With movement on the Navigation controller, shooting and stabbing on the Move, and fiddly stuff like inventory, map access and telling Shiva to please-stop-jogging-against-that-wall-people-are-starting-to-stare on the face buttons, Resident Evil 5 makes a lot of sense. On top of that, Capcom offers two different control configurations, which flip "locate partner" and "run/quick turn" between L1 and X depending on how your brain is wired up.
It's quirky, though. Rather than being used to, you know, fire the gun, the Move's trigger locks you in position and brings up the aiming reticule, and you then shoot with a stab of the Move button on top of the controller. It works better than it sounds, but with no second stick, you're still going to have to aim and stop moving if you want to look about very much. Some won't like the fact that you can't nudge the screen around at all by moving the targeting reticule to the edge (with gun drawn, the only way to move the screen is to use the left stick), but it does means you don't get that juddery feel a lot of motion-control shooters have whenever aiming and the camera are tied together. It's not as much of a problem as it sounds, really.
You can tweak sensitivities and enjoy some fairly pedestrian gestural stuff, mostly involving shaking (guess when) if you want to, but, while it all works well enough, you may still be left with a nagging feeling that shooters and motion controllers don't really fit together that naturally most of the time, no matter how well-intentioned everything is.
http://www.eurogamer.net/articles/2010-09-17-your-move-article?page=2