Hmm I'm playing it right now by capping it to 30fps through RTSS and borderless window. Just the odd hiccup here and there which I guess is due to the game loading new area.
I'm using GTX780 which I overclocked by 6% and so far it is stable. Not sure if I want to move the PhysX calculation to CPU.
Try it, i literally didn't notice any difference at all with anything else other than it being smoother and more frames. Defo worth a few tests i would say