"The enemy is neither a zombie nor ganado. Takeuchi described them to be 'human-like with intelligence'. From the shots, we can see a massive amount of enemies on screen. In comparison to '4', the enemies behave closest to the ganado in the village. What is Chris fighting for? Actually, these screens were shown over at the E3 event. In the trailer, Chris mumble to himself 'what am I fighting for?' Maybe his inner thought is one of the things that the game will be portraying."
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"When we were thinking what to do for a new generation Biohazard game, we always look at Shinji Mikami's '4'. That game is like the peak of the series, that seems like a wall so high that you think it's totally impossible to pass it. When we think of how to 'give birth' to '5', we realised we have to stop having the idea of just following his footsteps. In that case, even if we used '4' game system, we will have the hardship of adding in new elements, which is where we will spend most of our time on. After playing this game, I think everyone will feel as if they have just completed '4' for the first time again."
Those 2 statements scare the hell out of me. While many people seem to think RE4 was the greatest in the series, it's still by far the worse in the series simply because it betrayed everything that was great about Resident Evil and turned it into a run & gun fest (Albiet a good one) with no horror what so ever. It wasn't bad game at all, just a terrible Resident Evil. To say about 5 that "It'll feel as if they completed '4' for the first time again" makes me want to steer away from a purchase already.
I like the whole setting and the appearence of these new creatures, but dear God, I do NOT want any more Ganado type creatures, they're just not scary or interesting. Hopefully this new virus (or whatever it is) makes them similar to 28 days later type creatures (zombie-like and fast), which would be a nice step up from Ganado's. I'll reserve complete judgement for the game until I actually get to see some gameplay, but those interviews are already making me weary.