If Cole's in the game, I want him to have reinvented himself to hide from the public eye and look like the remodeled version that Sucker Punch almost used for InFamous 2.
And I don't want Fetch to die, because it's about time the protagonist from an InFamous game got to stick with the love interest for the whole game. Instead, when her life inevitably gets threatened, I want Delsin to give up his life to save hers, at the same time somehow transferring his power to her or something.
In the sequel, InFamous: Fetch Quest, you play as the spunky purple-haired bioterrorist in the rebuilt Empire City, looking for the remains of the First Sons in the hopes of being able to rebuild the ray sphere, or do the funky time travel thing Kessler did so she can save Delsin from dying. Only problem is he chooses to be evil, and not save her. Dun dun dun!
In the final game of the series, we pick back up with Zeke Jedediah Dunbar, who isn't a bioterrorist as you'll recall. But because he helped Cole in saving the world, he was awarded with enough money to become something in between Tony Stark and Bruce Wayne. He's come a long way from making faulty batteries and melee amps, and builds for himself some sort of anti-conduit suit that allows him to take down the revived-and-evil Delsin in Washington DC, because yes, Delsin is the ultimate anarchist rebel has taken over the government. The idea is Delsin won't be able to take Zeke's powers, so Zeke might be able to best him.
But Delsin is the better fighter, so he knocks out Zeke in his suit like it's nothing. Victorious, Delsin is about to deliver the killing blow, but then his brother Reggie springs into the scene and jumps between him and Zeke. To get to Zeke, Delsin is going to have to kill his own brother. Zeke gets up and starts to move around, and Reggie stays in front of him like a shield. Staying in motion to avoid Delsin's flank attacks, Zeke manages to reform his broken suit into another RFI, taking his knowledge from the last time. As a last ditch effort, Zeke sets off the RFI, killing Delsin and all the other bioterrorists.
Delsin's body explodes in a plume of smoke, and, as the particles rise up into the air, they form what might kind of vaguely look like a question mark.