Yes. As Nirolak and I implied, the question is far more likely to do with which races will be playable in the campaign, not which species will appear outright in the narrative.
BioWare has been quite upfront that multiple playable species is one of the most hotly requested additions to the series, something they explored thoroughly with Mass Effect 3's multiplayer (which had basically every major species). But realistically there's no way they can make all of the species playable in the campaign, considering the workload of modelling/texturing/animating character/armour/weapon/cinematic variables, dialogue alterations, additional voice work/filtering, and so on.
So, if we're going to play as multiple species, they're going to have to keep it limited. And if Dragon Age: Inquisition is used as reference point, four playable species in single player would be the sweet spot.
Humans are a given. That leaves (including B-tier species) Asari, Turian, Salarian, Krogan, Quarian, Geth, Drell, Batarian, Vorcha, and Volus. Cut it down to Asari, Turian, Salarian, Krogan, and Quarian to cover the "main species" and you're still two species too many. Gonna have to plan to cut two, people are going to be shitty either way, so you might as well go to the fans and see what the lower percentage of fan rage would be. Asari and Turian would be incredibly safe guarantees, in my opinion, so that leaves one opening.
This is assuming they actually do this, of course.