Well... Okay... that we know of.
I'm assuming you guys are going to be too busy elsewhere for the next couple of years or so, so at the very least this'll likely be the last for quite some time... no?
Insomniac has multiple studios and easily enough resources to work on more than one game at a time.
The real question here is if they still have the R&C magic. Resistance was a hit and miss franchise with different strengths and weaknesses with each iteration. Fuse felt like it lacked inspiration and was a paint by numbers shooter. Full Frontal Assault and All 4 One weren't particularly good either.
Into the Nexus is back to their strengths so I'm optimistic that it'll be more Crack in Time/Tools of Destruction, but will they carry that over into another trilogy on PS4, and will the sales of Into the Nexus support that?
The biggest disappointment for me was FFA. That game could have been great, but in the end was a less enjoyable experience than Orcs Must Die as a 3rd person action/shooter + tower defense hybrid.