I would really love a bold ME game about colonialism that would give the player real choices and shades of grey between each choice.
However knowing bioware if they're actually trying to tackle a topic this charged it wont be anywhere near interesting, just something horribly preachy. Political tensions are high enough that I'd never trust bioware not to constantly make sure that the player knows what they consider the morally right option instead of letting the player think for himself/herself.
How amazing would it be to make a decision between the welfare of your crew and a welfare of some peaceful and powerless race, witness the consequences of your choice and deal with the fallout throughout the game, both negatives and positives on all sides.
But instead it's gonna be: You made the red choice, now have +6 "evil" points and listen to admiral Hackett jr. explain in a single sentence that alien race X didn't like that you took their space mangos. Now let's forget that any of that happened and move on to a different planet with space pineapples to steal.
http://i.imgur.com/TWIEkYl.jpg
And yes, pls bioware let us go all Javik on all the primitives and give them a "choice".
No half assed "angry lovable renegade guy shepard" only nonsense, full on evil options included too.