Just so I'm not constantly hating on Bioware/Mass Effect/Dragon Age, even though they fully deserve it, I'll say I'm genuinely looking forward to the following from Mass Effect 3:
- Character interactions - characterization and dialogue are generally-speaking something that, as low as Bioware has fallen, they can still consistently do pretty well, and occasionally very well
- Clint Mansell - hell yes. Probably the best decision Bioware has made since whatever they did during Baldur Gate 2's development
- the Codex - always well-written, detailed, and fun to read
- the general ambiance - Space opera games aren't too common outside of Mass Effect, and I'm a sucker for all sorts of sci-fi
Gameplay and main plot I have no real expectations/hopes, except that the former will once again basically be third-person shooter. I expect choices made in ME2 to have no meaningful impact at all, and C&C in ME3 to again strictly follow the binary paragon/renegade model. I expect elements like exploration and loot to be without any real substance.
If Bioware can surprise the people greatly disappointed with a series that once held so much promise, that'd be swell. Their priorities seem pretty misplaced, though, to say the least.