I'm all up for removing DRM that doesn't work, but what would be the point of not using something that works?
It is the same argument that has to be considered with all DRM, the potential for negative impact upon your honest customers.
In that particular regard though Denuvo seems to be among the least noticeable/problematic.
An argument could also be made that the licensing fees for Denuvo could be instead spent elsewhere, on perhaps making the game better, etc.
Unfortunately it is very, very hard(impossible?) to accurately quantify how much impact piracy has upon sales. Without that info you can't really say what Denuvo is "worth" to a developer/publisher and without being able to pinpoint that value you can't really make a case on saying that value is too much/little compared to the negative impact upon your honest customers, IMHO.
I can't fault publishers for feeling they need effective DRM any more than I can fault honest customers for disliking the negative impacts of DRM on their experience. That said, if it weren't for the pirates themselves none of this would be necessary so it seems obvious where the blame/fault lies.