The realtime nature of PD's gameplay makes it very different from all other CCGs though, and personally I think that is a big part of what makes it so niche.
Most CCG fans aren't big fans of fast paced action games. Most fans of fast paced action games aren't fans of CCGs. PD's audience is basically the incredibly small group of us out there who like basically every kind of game (video, card, board, etc.) under the sun if it's unique and stimulating.
Then you need to subtract the people from those groups who are too entrenched in their current/upcoming CCG (Magic, Scrolls, Hearthstone, etc.) to give this a real shot.
It could maybe tap in to the MOBA audience, but again that's a pretty full genre.
Basically, other than an absolutely microscopic group of people who really loved the original this game won't sell a single person an Xbox One and will have to fight for recognition within the already existing userbase. As PD without multi isn't really a game worth playing that likely leaves it in a danger zone of not having a consistent enough player base to stay alive for long after release.
We'll see. I personally feel like PD tapped into a lot of very interesting ideas that many games since have ran with (the MOBAs, Anarchy Reigns, computer based CCG implementation, Transistor's configuration system, etc.), but I just don't see what is going to be dramatically different this time. Are people more receptive to the genres it hybridizes? Sure, but that's a product of a much more crowded field.
I'm probably just too skeptical as I continue to have the sneaking suspicion that MS basically dumped this in Futatsugi's/Grounding's lap when they finished Crimson Dragon last fall and told them to get it out ASAP in order to have an old IP alongside Crackdown to brag about servicing the core with. I need a lot more details before I view this as a genuine effort to revitalize the IP and not just a move to gain temporary favor with internet message boards.