Yes, but tends to happen less in games that make lighter use of triggers and shoulder buttons, which makes me able to play them longer (or with much less discomfort) - So it's clear to me shoulder buttons contribute to this discomfort. Is there an alternative? I don't know, but why is everyone in this thread so quick to shut down any discussion on the topic?
well for one, because the design is obviously not going to change for PS/Xbox
So you might as well get used to it.
Also it's clear to me that this is one of those 2%-er type issues, where you and the OP are in a very small minority. Does not mean that your "opinion" is invalid, it just means that no change will come about from it.
It's like people who vote for Ron Paul or no-name independents for US President. They are free to do so, but it does not mean the country should enact their policies just because 2% of people vote for them. Majority rules.