this gen: none, nada, nichts, zero
previous gens:
Meche from Grim Fandango
and maybe Sam from The Getaway Black Monday
I think sexualizing starts when the main character or NPC is expected/has to be (overly) beautiful to be considered strong and noteworthy. Back in the days technology was the limiting factor but what's wrong with adding some "imperfections" with today's tech? You know like giving them "normal" sized breasts, don't make them ass monster for once or more face specific, add some dark circles under the eyes or how about eye bags, lines, beauty spots (birthmarks, sunspots, brown dots or whatever you call them) etc. you name it.
Even people who are considered pretty (in real life) have to deal with their fair share of blemishes. That's why most female videogame character still look like lifeless barbie dolls to me. Videogame artists don't seem to have any problems making their male counterparts all rough and wrinkly, so it's definitely not a hardware-limitation issue.
And don't get me started about the actual persona and characteristics of female characters in videogames. Pretty much all of them seem to have the mindset of a 12 year old girl or worse.
It's so sad that you really have to think hard to come up with something. Well, some will argue that videogames are still a new medium... but to be honest, gaming really isn't anymore.
// also, I had a good laugh at all the guys who posted the uncharted bubble butt monster Chloe