Agreed. I thought those lines were funny, though.
I don't think it's supposed to be funny because the viewer thinks, "Oh wow, it's so funny to tell a woman she's disgusting!" I think it's supposed to be funny because it's over the top, and his culture is so unrelatably different. She's obviously cute, and Drax has a very strange sense of values for his romantic partners from what he describes.
In the first movie, when he calls Gamora a whore, I found that to be stupid, mysoginistic, and not funny. Telling Mantis, who I adored, that she was disgusting, was funny due to how off it is. Sounds like he likes larger women, so that's one of the major turnoffs for him. Hey, at least he's not reinforcing harmful female body image stereotypes.